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Title: Apelin – additional marker of insulin resistance
Authors: Журавльова, Лариса Володимировна
Шеховцова, Юлія Олександрівна
Zhuravlyova, L.V.
Shekhovtsova, Y.A.
Keywords: body mass index
increased body weight
type 2 diabetes mellitus
Issue Date: 2015
Citation: Zhuravlyova L. V. Apelin – additional marker of insulin resistance / L. V. Zhuravlyova, Y. A. Shekhovtsova // Reseach result. – 2015. – Vol. 1, № 1. – Р. 4–10.
Abstract: Summary: The purpose of the present study was to determine the correlations between the state of carbohydrate metabolism and concentrations of apelin in blood of patients with type 2 diabetes mellitus with different phenotypes. Materials and methods. A total of 32 patients with type 2 diabetes mellitus with different phenotypes (13 men, mean age 56,77 ± 1,79 years) were examined. The control group included 20 healthy individuals. Results. The significant elevation of adipocytokine apelin level was found. The significant correlations between body mass index, apelin and the parameters of carbohydrate metabolism were defined. Conclusions. Increased levels of apelin and connection between this adipocytokine and anthropometric parameters as well as indices of carbohydrate metabolism suggests that elevated body weight contributes to activation and strengthening of impact mechanisms of adipose tissue hormones on metabolic status
Appears in Collections:Наукові праці. Кафедра внутрішньої медицини № 3 та ендокринології

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