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Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/23159

Название: Pathogenetic mechanisms of experimental gingivitis progression under the influence of lipopolysaccharide
Авторы: Sokolova, Iryna
Skydan, Karyna
Skydan, Maksym
Levitskiy, Anatoliy
Slynko, Yuliya
Ключевые слова: gingivitis
periodontal disease
experimental model
experimental animals
Issue Date: 2019
Библиографическое описание: Pathogenetic mechanisms of experimental gingivitis progression under the influence of lipopolysaccharide / I. I. Sokolova, M. I. Skydan, A. P. Levitskiy, Y. A. Slynko // Світ медицини та біології. – 2019. – № 1 (67). – C. 187–190.
Аннотация: The paper presents the results of patogenetic rationale for the use of gel with lipopolysaccharide for gingivitis modelling. It shows, that lipopolysaccharide applications lead to significant increase in activity of elastase by 26.8%, malonic dialdehyde by 32.8%, urease by 78.9%, degree of dysbiosis by 32.6%, decrease in activity of lysozyme by 57.6% and antioxidant-prooxidant index by 29.7%. Thus, lipopolysaccharide application leads to the progression of inflammation processes in gums of experimental animals, dysbiosis and oxidative stress, that is pathogenetic links of gingivitis progression in humans as well.
URI: http://repo.knmu.edu.ua/handle/123456789/23159
Appears in Collections:Наукові праці. Кафедра стоматології

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