DSpace About DSpace Software DSpace
 

Repository KhNMU >
Кафедри >
Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки >
Наукові праці. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки >

Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/21630

Название: Polymorphism of the renin-angiotensin system genes and endothelial no-synthase gene in obese patients with arterial hypertension
Авторы: Ashcheulova, Tatiana
Gerasimchuk, Nina
Demydenko, Ganna
Kulikova, Mariya
Ключевые слова: endothelial nitric oxide synthase
renin-angiotensin system
gene polymorphism
hypertonic disease
obesity
Issue Date: Dec-2018
Библиографическое описание: Polymorphism of the renin-angiotensin system genes and endothelial no-synthase gene in obese patients with arterial hypertension / T. V. Ashcheulova, N. N. Gerasimchuk, G. V. Demydenko, M. V. Kulikova // Biopolymers and Cell. – 2018. – Vol. 34, N 5. – P. 331–349. – doi: http://dx.doi.org/10.7124/bc.000988.
Аннотация: The review is dedicated to relationships between the blood pressure and body mass. Endothelial dysfunction and imbalance of neurohumoral systems, namely, the pathological increase in the activity of the renin-angiotensin system, in combination with obesity are the main mechanisms of the of the hypertonic disease pathogenesis. Here we discuss the research on polymorphism of the renin angiotensinic system genes and the endothelial synthase nitric oxide gene. The difficulty lies in the correct assessment of associations of alleles which have clinical signifi- cance. It is essential to determine precisely the associations of gene polymorphisms in the hypertonic disease with obesity. This provides an opportunity to identify new personified approaches to the treatment of patients with this complex pathology.
URI: http://repo.knmu.edu.ua/handle/123456789/21630
Appears in Collections:Наукові праці. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки

Files in This Item:

File Description SizeFormat
BaC_#5_2018_Ashcheulova.pdf400,7 kBAdobe PDFView/Open


This item is protected by original copyright

View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback