Please use this identifier to cite or link to this item:
http://repo.knmu.edu.ua/handle/123456789/17202
Title: | Rapid diagnostics of urinary iodine using a portable EDXRF spectrometer |
Authors: | Mikhailov, I. Baturin, A. Mikhailov, A. Borisova, S. Reshetnyak, M. Galata, D. |
Keywords: | X-ray fluorescence spectrum selective excitation urinary iodine rapid diagnostics |
Issue Date: | 2017 |
Citation: | Rapid diagnostics of urinary iodine using a portable EDXRF spectrometer / I. F. Mikhailov, A. A. Baturin, A. I. Mikhailov [et al.] // Journal of X-Ray Science and Technology. – 2017. – № 25. – P. 515–521. |
Abstract: | A method for urinary iodine diagnostics using a portable energy-dispersion X-ray fluorescent (EDXRF) spectrometer is proposed. The principle of the method consists in excitation of the sample atoms fluorescence by the energy spectrum intentionally formed from the spectrum of an X-ray tube using an optimized X-ray scheme. The optimization by the criterion of the minimum detection limit for L-series iodine fluorescence lines included the calculation of optimal atomic numbers for materials of a re-radiator and a filter, and their thicknesses, the collimation system parameters, and an X-ray tube voltage. Experimentally achieved detection limits were 45 and 75 g/L by I-L and I-L lines, respectively, at the theoretically extreme value 30 g/L. This sensitivity is found to be sufficient for urinary iodine diagnostics in the range from 50 to 200 g/L. The results obtained from different patients have shown the satisfactory convergence for the iodine concentration determination by L and I-L fluorescence lines. The simple sample preparation procedure and comparably small sizes of the apparatus allows rapid researches directly in clinical settings. |
URI: | https://repo.knmu.edu.ua/handle/123456789/17202 |
Appears in Collections: | Наукові праці. Кафедра патологічної анатомії |
Files in This Item:
File | Description | Size | Format | |
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urine iodine-GALATA.pdf | 196,04 kB | Adobe PDF | View/Open |
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