The effect of surface treatment of ceramic oxide coatings deposited by magnetron sputtering method on the adhesive and proliferative activity of mesenchymal stem cells

Abstract

The effect was analyzed of surface treatment by argon ions on the surface properties of tantalum pentoxide coatings deposited by reactive magnetron sputtering. The structural pa-rameters of the as-deposited coatings were investigated by means of transmission electron mi-croscopy, atomic force microscopy and scanning electron microscopy. X-ray diffraction pro-files and X-ray photoelectron spectra were also acquired. The total surface free energy (SFE), the polar, dispersion parts and fractional polarities, were estimated by the Owens-Wendt-Rabel-Kaeble method. The adhesive and proliferative potentials of bone marrow cells were evaluated for both Ta2O5 coatings and Ta2O5 coatings deposited by simultaneous bombardment by argon ions in in vitro tests.