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Title: | Prognostic value of polymorphism of G-308A gene of the tumor necrosis factor-αin the progression of chronic heart failure in patients with ischemic heart disease and obesity |
Authors: | Кравчун, Павло Григорович Кадикова, Ольга Ігорівна Риндіна, Наталія Геннадіївна Крапівко, Світлана Олександрівна Kravchun, Pavlo G. Kadykova, Olga Ryndina, Natalia Krapivko, Svitlana |
Keywords: | ischemic heart disease obesity сhronic heart failure G-308A gene of tumor necrosis factor-α polymorphism |
Issue Date: | 2016 |
Citation: | Prognostic value of polymorphism of G-308A gene of the tumor necrosis factor-αin the progression of chronic heart failure in patients with ischemic heart disease and obesity / P. Kravchun, O. Kadykova, N. Ryndina, S. Krapivko // Archive of Clinical Medicine. – 2016. – Vol. 22, No. 1. – Р. 88–92. |
Abstract: | The goal - to evaluate the role of polymorphism of G-308A gene tumor necrosis factor - α as a possible factor in the progression of chronic heart failure in patients with coronary heart disease and obesity. Conclusions. The presence of allele A and A / A genotype polymorphic locus G-308A TNF-α gene in patients with coronary artery disease with concomitant obesity was associated with progression of CHF, the formation of LV systolic dysfunction. |
URI: | https://repo.knmu.edu.ua/handle/123456789/14564 |
Appears in Collections: | Наукові праці. Кафедра внутрішньої медицини № 2 і клінічної імунології та алергології ім. ак. Л.Т. Малої |
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