Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/13639
Title: Structural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A)
Authors: Кравчун, Павло Григорович
Кадикова, Ольга Ігорівна
Риндіна, Наталія Геннадіївна
Крапівко, Світлана Олександрівна
Молотягін, Дмитро Геннадійович
Kravchun, P.G.
Kadykova, O.I.
Ryndina, N.G.
Krapivko, S.O.
Molotiagin, D.G.
Keywords: polymorphism
gene of tumor necrosis factor-α
coronary heart disease
obesity
Issue Date: 2016
Citation: Structural functional parameters of the heart in patients with coronary heart disease with concomitant obesity depending on genotypes of gene of tumor necrosis factor-α (G-308A) / P. G. Kravchun, O. I. Kadykova, N. G. Ryndina, S. O. Krapivko, D. G. Molotiagin // British Journal of Educational and Scientiic Studies. – 2016. – Vol. 12, № 1 (23), January–June. – P. 864–871.
Abstract: The article deals with influence of different genotypes of gene of tumor necrosis factor-α on changes of structure and function of the myocardium in patients with coronary heart disease with concomitant obesity by means of examination of 222 patients. Conclusions. In patients with coronary heart disease (CHD) and obesity with genotype A/A of TNF-α gene (G-308A) more significant disorders in structure and function of the myocardium are observed, that is increased dimensions of the left ventricle, its mass associated with reduced contraction ability, which results in unfavorable left ventricle remodeling and development of diastolic dysfunction of the left ventricle.
URI: http://repo.knmu.edu.ua/handle/123456789/13639
Appears in Collections:Наукові праці. Кафедра внутрішньої медицини № 2 і клінічної імунології та алергології ім. ак. Л.Т. Малої

Files in This Item:
File Description SizeFormat 
Кадикова в British Journal.doc265 kBMicrosoft WordView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.