Clinical significance of ultrasonography in evaluation of morphofunctional state of liver and portohepatolienal bloodstream in chronic diffuse liver diseases

Abstract

Abstract: In randomized three-phase prospective cohort controlled research which included 2564 persons with chronic diffuse liver diseases (1865 cases of fatty liver disease, 462 cases of chronic hepatitis, 100 cases of liver cirrhosis) and 137 healthy controls, the clinical significance of ultrasonography in quantitative evaluation of liver parenchyma morphofunctional state and portohepatolienal bloodstream in patients with chronic diffuse liver diseases was estimated. Twenty-seven ultrasound and two additional, derived from laboratory tests index parameters were testified for the grounding to be included into diagnosis-prognostic algorithm for patients with this pathology, which has been developed, validated and recommended for practical application. Further perspectives are related to fundamental logico-statistical analysis of the data for development of mathematic model of pathologic process and its application to practical health care service.